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Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection.
Pezoldt, Joern Pisano, Fabio Heine, Wiebke Pasztoi, Maria Rosenheinrich, Maik Nuss, Aaron M Pils, Marina C Prinz, Immo Förster, Reinhold Huehn, Jochen
Pezoldt, Joern
Pisano, Fabio
Heine, Wiebke
Pasztoi, Maria
Rosenheinrich, Maik
Nuss, Aaron M
Pils, Marina C
Prinz, Immo
Förster, Reinhold
Huehn, Jochen
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Issue Date
2017-09-15
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Abstract
To successfully limit pathogen dissemination, an immunological link between the entry tissue of the pathogen and the underlying secondary lymphoid organs (SLOs) needs to be established to prime adaptive immune responses. Here, the prerequisite of CCR7 to mount host immune responses within SLOs during gastrointestinal Yersinia pseudotuberculosis infection to limit pathogen spread was investigated.
Citation
Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection. 2017, 216 (6):752-760 J. Infect. Dis.
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en
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1537-6613