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Your Base Editor Might Be Flirting with Single (Stranded) DNA: Faithful On-Target CRISPR Base Editing without Promiscuous Deamination.

Collins, Scott P
; 
Beisel, Chase L
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Issue Date
2020-09-03
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Abstract
Jin et al. (2020) engineered new variants of CRISPR base editors that make precise genomic edits in rice protoplasts while minimizing untargeted mutagenesis.
Citation
Mol Cell. 2020 Sep 3;79(5):703-704. doi: 10.1016/j.molcel.2020.07.030.
Affiliation
HIRI, Helmholtz-Institut für RNA-basierte Infektionsforschung, Josef-Shneider Strasse 2, 97080 Würzburg, Germany.
Publisher
Elsevier
Journal
Molecular cell
URI
http://hdl.handle.net/10033/622492
DOI
10.1016/j.molcel.2020.07.030
PubMed ID
32888434
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Article
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Language
en
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1097-4164
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Attribution-NonCommercial-ShareAlike 4.0 International
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publications of the research group biology of synthetic RNA ([HIRI] RSYN)