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Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien.

Altendorfer, Mario
Irschik, Herbert
Menche, Dirk
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Issue Date
2012-09-01
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Abstract
Novel simplified side chains of the potent RNA polymerase inhibitor etnangien were designed, synthesized and evaluated for antibacterial activity against Gram-positive bacteria and one Gram-negative bacterium.
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Design, synthesis and biological evaluation of simplified side chains of the macrolide antibiotic etnangien. 2012, 22 (17):5731-4 Bioorg. Med. Chem. Lett.
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Article
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en
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1464-3405
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Archived with thanks to Bioorganic & medicinal chemistry letters