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Dengue-specific subviral nanoparticles: design, creation and characterization.
Khetarpal, Niyati Poddar, Ankur Nemani, Satish K Dhar, Nisha Patil, Aravind Negi, Priyanka Perween, Ashiya Viswanathan, Ramaswamy Lünsdorf, Heinrich Tyagi, Poornima
Khetarpal, Niyati
Poddar, Ankur
Nemani, Satish K
Dhar, Nisha
Patil, Aravind
Negi, Priyanka
Perween, Ashiya
Viswanathan, Ramaswamy
Lünsdorf, Heinrich
Tyagi, Poornima
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Abstract
Dengue is today the most significant of arboviral diseases. Novel tools are necessary to effectively address the problem of dengue. Virus-like particles (VLP) offer a versatile nanoscale platform for developing tools with potential biomedical applications. From the perspective of a potentially useful dengue-specific tool, the dengue virus envelope protein domain III (EDIII), endowed with serotype-specificity, host receptor recognition and the capacity to elicit virus-neutralizing antibodies, is an attractive candidate.
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Dengue-specific subviral nanoparticles: design, creation and characterization. 2013, 11 (1):15 J Nanobiotechnology
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en
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1477-3155
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Archived with thanks to Journal of nanobiotechnology