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Host cell mTORC1 is required for HCV RNA replication.

Stöhr, Stefanie
; 
Costa, Rui
; 
Sandmann, Lisa
; 
Westhaus, Sandra
; 
Pfaender, Stephanie
; 
Anggakusuma
; 
Dazert, Eva
; 
Meuleman, Philip
; 
Vondran, Florian W R
; 
Manns, Michael P
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2015-08-14
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Abstract
Chronically HCV-infected orthotopic liver transplantation (OLT) recipients appear to have improved outcomes when their immunosuppressive regimen includes a mammalian target of rapamycin (mTOR) inhibitor. The mechanism underlying this observation is unknown.
Citation
Host cell mTORC1 is required for HCV RNA replication. 2015: Gut
Affiliation
TWINCORE, Centre for Experimental and Clinical Infection Research; a joint venture between the Medical School Hannover (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany.
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Journal
Gut
URI
http://hdl.handle.net/10033/592833
DOI
10.1136/gutjnl-2014-308971
PubMed ID
26276683
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1468-3288
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publications of the research group virus transmission ([TC]VIRT)