Loading...
The NF-κB transcription factor c-Rel controls host defense against Citrobacter rodentium.
Luu, Maik Romero, Rossana Bazant, Jasmin Abass, Elfadil Hartmann, Sabrina Leister, Hanna Fischer, Florence Mahdavi, Rouzbeh Plaza-Sirvent, Carlos Schmitz, Ingo
Luu, Maik
Romero, Rossana
Bazant, Jasmin
Abass, Elfadil
Hartmann, Sabrina
Leister, Hanna
Fischer, Florence
Mahdavi, Rouzbeh
Plaza-Sirvent, Carlos
Schmitz, Ingo
Citations
Altmetric:
Advisors
Editors
Other Contributors
Issue Date
2019-11-14
Submitted date
Files
Loading...
original manuscript
Adobe PDF, 850.42 KB
Loading...
figure 1
TIFF, 357 KB
Loading...
figure 2
TIFF, 451.95 KB
Other Titles
Abstract
Mice lacking CD4+ T cells or B cells are highly susceptible to Citrobacter rodentium infection. In this study, we show that the activity of the transcription factor c-Rel in lymphocytes is crucial for clearance of C. rodentium. Mice deficient for c-Rel fail to generate protective antibodies and to eradicate the pathogen.
Citation
Eur J Immunol. 2019 Nov 14. doi: 10.1002/eji.201948314.
Publisher
Journal
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Other
Language
en
Description
Letter
Series/Report no.
ISSN
1521-4141
EISSN
ISBN
ISMN
Gov't Doc #
Sponsors
License
Attribution-NonCommercial-ShareAlike 4.0 International