Loading...
Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis.
Kanjarawi, Reem Dy, Michel Bardel, Emilie Sparwasser, Tim Dubois, Bertrand Mecheri, Salah Kaiserlian, Dominique
Kanjarawi, Reem
Dy, Michel
Bardel, Emilie
Sparwasser, Tim
Dubois, Bertrand
Mecheri, Salah
Kaiserlian, Dominique
Files
Loading...
Open Access publication
Adobe PDF, 803.79 KB
Other Titles
Abstract
Anaphylaxis is a life-threatening outcome of immediate-type hypersensitivity to allergen, consecutive to mast cell degranulation by allergen-specific IgE. Regulatory T cells (Treg) can control allergic sensitization and mast cell degranulation, yet their clinical benefit on anaphylactic symptoms is poorly documented. Here we investigated whether Treg action during the effector arm of the allergic response alleviates anaphylaxis.
Citation
Regulatory CD4+Foxp3+ T cells control the severity of anaphylaxis. 2013, 8 (7):e69183 PLoS ONE
Publisher
Journal
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
1932-6203
EISSN
ISBN
ISMN
Gov't Doc #
Sponsors
License
Archived with thanks to PloS one