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Toward Whole-Transcriptome Editing with CRISPR-Cas9.

Heckl, Dirk
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Charpentier, Emmanuelle
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2015-05-21
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Abstract
Targeted regulation of gene expression holds huge promise for biomedical research. In a series of recent publications (Gilbert et al., 2014; Konermann et al., 2015; Zalatan et al., 2015), sophisticated, multiplex-compatible transcriptional activator systems based on the CRISPR-Cas9 technology and genome-scale libraries advance the field toward whole-transcriptome control.
Citation
Toward Whole-Transcriptome Editing with CRISPR-Cas9. 2015, 58 (4):560-2 Mol. Cell
Affiliation
Helmholtz Centre for infection research, Inhoffenstr. 7, 38124 Braunschweig, Germany.
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Molecular cell
URI
http://hdl.handle.net/10033/620557
DOI
10.1016/j.molcel.2015.05.016
PubMed ID
26000839
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1097-4164
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publications of the department Regulation of infection