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Discovery of antiviral molecules for dengue: In silico search and biological evaluation.
Cabarcas-Montalvo, Maria Maldonado-Rojas, Wilson Montes-Grajales, Diana Bertel-Sevilla, Angela Wagner-Döbler, Irene Sztajer, Helena Reck, Michael Flechas-Alarcon, Maria Ocazionez, Raquel Olivero-Verbel, Jesus
Cabarcas-Montalvo, Maria
Maldonado-Rojas, Wilson
Montes-Grajales, Diana
Bertel-Sevilla, Angela
Wagner-Döbler, Irene
Sztajer, Helena
Reck, Michael
Flechas-Alarcon, Maria
Ocazionez, Raquel
Olivero-Verbel, Jesus
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Issue Date
2016-03-03
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Abstract
Dengue disease is a global disease that has no effective treatment. The dengue virus (DENV) NS2B/NS3 protease complex is a target for designing specific antivirals due to its importance in viral replication and its high degree of conservation.
Citation
Discovery of antiviral molecules for dengue: In silico search and biological evaluation. 2016, 110:87-97 Eur J Med Chem
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Article
Language
en
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ISSN
1768-3254