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Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase.
TrehanPati, Nirupma Sukriti, Sukriti Geffers, Robert Hissar, Syed Toepfer, Tanja Guzman, Carlos A Sarin, Shiv Kumar
TrehanPati, Nirupma
Sukriti, Sukriti
Geffers, Robert
Hissar, Syed
Toepfer, Tanja
Guzman, Carlos A
Sarin, Shiv Kumar
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2011-06
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Abstract
Approximately 50% of acute viral hepatitis in young adults and in pregnant women is due to hepatitis E virus (HEV) infection in developing countries. T cell-mediated immune injury probably plays a key role in the pathogenesis of acute hepatitis illness. However, there is a paucity of data on the global gene expression programs activated on T cells, which are subsequently responsible for T cell recruitment to the liver and triggering of immune injury.
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Gene expression profiles of T cells from hepatitis E virus infected patients in acute and resolving phase. 2011, 31 (3):498-508 J. Clin. Immunol.
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en
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1573-2592
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Archived with thanks to Journal of clinical immunology