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Groundwater, soil and compost, as possible sources of virulent and antibiotic-resistant Pseudomonas aeruginosa.
Kaszab, Edit Radó, Júlia Kriszt, Balázs Pászti, Judit Lesinszki, Virág Szabó, Ádám Tóth, Gergő Khaledi, Ariane Szoboszlay, Sándor
Kaszab, Edit
Radó, Júlia
Kriszt, Balázs
Pászti, Judit
Lesinszki, Virág
Szabó, Ádám
Tóth, Gergő
Khaledi, Ariane
Szoboszlay, Sándor
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2019-11-18
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Abstract
Pseudomonas aeruginosa is a major public health concern all around the world. In the frame of this work, a set of diverse environmental P. aeruginosa isolates with various antibiotic resistance profiles were examined in a Galleria mellonella virulence model. Motility, serotypes, virulence factors and biofilm-forming ability were also examined. Molecular types were determined by pulsed-field gel electrophoresis (PFGE). Based on our results, the majority of environmental isolates were virulent in the G. mellonella test and twitching showed a positive correlation with mortality. Resistance against several antibiotic agents such as Imipenem correlated with a lower virulence in the applied G. mellonella model. PFGE revealed that five examined environmental isolates were closely related to clinically detected pulsed-field types. Our study demonstrated that industrial wastewater effluents, composts, and hydrocarbon-contaminated sites should be considered as hot spots of high-risk clones of P. aeruginosa.
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Int J Environ Health Res. 2019 Nov 18:1-13. doi: 10.1080/09603123.2019.1691719.
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en
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1369-1619
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Attribution-NonCommercial-ShareAlike 4.0 International