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BIOSENSORS FOR THE DETECTION OF HEAVY METAL IONS
Hilpert, Reinhold Zenk, Meinhart H. Binder, Florian
Hilpert, Reinhold
Zenk, Meinhart H.
Binder, Florian
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Issue Date
1989
Submitted date
2024-01-16
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Abstract
A concept for the development of biosensors for the detection of heavy metal ions in aquaeous solution is introduced. Phytochelatins, metallothioneins and glutathione are used as biological components for the heavy metal sensors. These peptides/proteins selectively bind heavy metal ions via thiolate complex formation. The biological component is immobilized at the surface of an appropriate transducer. Changes within the layer of immobilized peptides/proteins, effected by binding of metal ions (e.g. release of protons, changes of mass and optical properties), are transformed into electrical signals by the transducer (proton-sensitive field effect transistor, resonating piezoelectric crystal or optical device). Preliminary experiments demonstrate the suitability of phytochelatins and glutathione as biological components for the development of biosensors for heavy metals.
Citation
Biosensors : applications in medicine, environmental protection and process control, 367 - 370
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Type
Book chapter
conference paper
conference paper
Language
en
Description
Series/Report no.
GBF monographs ; Volume 13
ISSN
0930-4320
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ISBN
3527280324
0895739550
0895739550
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Attribution-NonCommercial-ShareAlike 4.0 International