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BIOSENSOR SYSTEMSUTILIZING NADH AS AN INTERMEDIATE

Risinger, Lars
Skoog, Mikael
Yang, Xiurong
Moges, Ghirma
Johansson, Gillis
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Issue Date
1992
Submitted date
2024-05-08
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Abstract
The combination of dehydrogenases and chemically modified graphite electrodes has proved particularly useful in the developmentof highly selective and sensitive biosensor systems. Amongthe applications given is a flow injection system for the determination of fructose with a linear range of 1 pM - 2 mM.As a means toincrease sensitivity further, substrate recycling was employed in the determination of ATP down to the nano-molar level. A creatine and creatinine assayillustrates the potential of coupled equilibria and coimmobilized enzymes. For the determination ofglucose in whole blood a dialyzer was integrated with a biosensor. The hematocrit dependence on the transfer of glucose through the dialysis membrane was studied.
Citation
Biosensors : fundamentals, technologies and applications, 505 - 510
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Type
Book chapter
conference paper
Language
en
Description
Series/Report no.
GBF monographs ; Volume 17
ISSN
0930-4320
EISSN
ISBN
1560812206
3527284370
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Attribution-NonCommercial-ShareAlike 4.0 International