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A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine.

Svindland, Signe C
; 
Pedersen, Gabriel K
; 
Pathirana, Rishi D
; 
Bredholt, Geir
; 
Nøstbakken, Jane K
; 
Jul-Larsen, Åsne
; 
Guzmán, Carlos A
; 
Montomoli, Emanuele
; 
Lapini, Giulia
; 
Piccirella, Simona
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Issue Date
2013-11
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Abstract
Highly pathogenic avian influenza A/H5N1 virus remains a potential pandemic threat, and it is essential to continue vaccine development against this subtype. A local mucosal immune response in the upper respiratory tract may stop influenza transmission. It is therefore important to develop effective intranasal pandemic influenza vaccines that induce mucosal immunity at the site of viral entry.
Citation
A study of Chitosan and c-di-GMP as mucosal adjuvants for intranasal influenza H5N1 vaccine. 2013, 7 (6):1181-93 Influenza Other Respir Viruses
Affiliation
department of vaccinology and applied microbiology, Helmholtz Centre for infection research, D38124 Braunschweig, Germany
Publisher
Journal
Influenza and other respiratory viruses
URI
http://hdl.handle.net/10033/311297
DOI
10.1111/irv.12056
PubMed ID
23170900
PubMed Central ID
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Article
Language
en
Description
Series/Report no.
ISSN
1750-2659
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Archived with thanks to Influenza and other respiratory viruses
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publications of the research group vaccinology and applied microbiology (VAC)