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Dynamic Proteoids Generated From Dipeptide-Based Monomers.

Liu, Yun
; 
Stuart, Marc C A
; 
Buhler, Eric
; 
Hirsch, Anna K H
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2018-05-28
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Abstract
Dynamic proteoids are dynamic covalent analogues of proteins which are generated through the reversible polymerization of amino-acid- or peptide-derived monomers. The authors design and prepare a series of dynamic proteoids based on the reversible polycondensation of six types of dipeptide hydrazides bearing different categories of side chains. The polymerization and structures of biodynamers generated by
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HIPS, Helmholtz-Institut für pharmazeutische Forschung Saarland, Universitätscampus 8.1, 66123 Saarbrücken, Germany.
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http://hdl.handle.net/10033/621402
DOI
10.1002/marc.201800099
PubMed ID
29806088
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1521-3927
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Attribution-NonCommercial-ShareAlike 3.0 United States
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publications of the research group drug design and optimization(HIPS]DDOP)