Loading...
Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds.
Axenov-Gibanov, Denis V Voytsekhovskaya, Irina V Tokovenko, Bogdan T Protasov, Eugeniy S Gamaiunov, Stanislav V Rebets, Yuriy V Timofeyev, Maxim A
Axenov-Gibanov, Denis V
Voytsekhovskaya, Irina V
Tokovenko, Bogdan T
Protasov, Eugeniy S
Gamaiunov, Stanislav V
Rebets, Yuriy V
Timofeyev, Maxim A
Files
Loading...
Open Access publication
Adobe PDF, 409.03 KB
Other Titles
Abstract
Actinobacteria isolated from unstudied ecosystems are one of the most interesting and promising sources of novel biologically active compounds. Cave ecosystems are unusual and rarely studied. Here, we report the isolation and characterization of ten new actinobacteria strains isolated from an ancient underground lake and moonmilk speleothem from the biggest conglomeratic karstic cave in Siberia with a focus on the biological activity of the obtained strains and the metabolite dereplication of one active strain. Streptomyces genera isolates from moonmilk speleothem demonstrated antibacterial and antifungal activities. Some of the strains were able to inhibit the growth of pathogenic Candida albicans.
Citation
Actinobacteria Isolated from an Underground Lake and Moonmilk Speleothem from the Biggest Conglomeratic Karstic Cave in Siberia as Sources of Novel Biologically Active Compounds. 2016, 11 (2):e0149216 PLoS ONE
Publisher
Journal
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
1932-6203