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Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus.

Stentzel, Sebastian
Teufelberger, Andrea
Nordengrün, Maria
Kolata, Julia
Schmidt, Frank
van Crombruggen, Koen
Michalik, Stephan
Kumpfmüller, Jana
Tischer, Sebastian
Schweder, Thomas
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2017-02
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Abstract
A substantial subgroup of asthmatic patients have "nonallergic" or idiopathic asthma, which often takes a severe course and is difficult to treat. The cause might be allergic reactions to the gram-positive pathogen Staphylococcus aureus, a frequent colonizer of the upper airways. However, the driving allergens of S aureus have remained elusive.
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Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. 2017, 139 (2):492-500.e8 J. Allergy Clin. Immunol.
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Article
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en
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1097-6825
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