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Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011.
Balabanova, Yanina Klar, Stefanie Deleré, Yvonne Wilking, Hendrik Faber, Mirko S Lassen, Sofie Gillesberg Gilsdorf, Andreas Dupke, Susann Nitschke, Martin Sayk, Friedhelm
Balabanova, Yanina
Klar, Stefanie
Deleré, Yvonne
Wilking, Hendrik
Faber, Mirko S
Lassen, Sofie Gillesberg
Gilsdorf, Andreas
Dupke, Susann
Nitschke, Martin
Sayk, Friedhelm
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Abstract
The largest known outbreak caused by a rare hybrid strain of Shiga toxin-producing E.coli (STEC) and enteroaggregative E. coli (EAEC) (E.coli O104:H4) of serotype O104:H4 occurred in Germany in 2011. Fenugreek sprouts acted as a transmission vehicle and were widely consumed in the outbreak area at the time of the epidemic. In total 3,842 people developed a clinical illness caused by this strain; however the rates of asymptomatic infections remain unclear. We aimed to develop a serological assay for detection of E.coli O104 LPS specific antibodies and to establish the post-outbreak levels of seropositivity among people with documented exposure to contaminated sprouts.
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Serological Evidence of Asymptomatic Infections during Escherichia coli O104:H4 Outbreak in Germany in 2011. 2013, 8 (9):e73052 PLoS ONE
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1932-6203
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