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Data-driven assessment of eQTL mapping methods.

Michaelson, Jacob J
; 
Alberts, Rudi
; 
Schughart, Klaus
; 
Beyer, Andreas
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2010
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Abstract
The analysis of expression quantitative trait loci (eQTL) is a potentially powerful way to detect transcriptional regulatory relationships at the genomic scale. However, eQTL data sets often go underexploited because legacy QTL methods are used to map the relationship between the expression trait and genotype. Often these methods are inappropriate for complex traits such as gene expression, particularly in the case of epistasis.
Citation
Data-driven assessment of eQTL mapping methods. 2010, 11:502 BMC Genomics
Affiliation
Cellular Networks and Systems Biology, Biotechnology Center - TU Dresden, Dresden, Germany.
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BMC genomics
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http://hdl.handle.net/10033/123291
DOI
10.1186/1471-2164-11-502
PubMed ID
20849587
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Article
Language
en
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1471-2164
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publications of the research group infection genetics (INFG)