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CONTINUOUS GLUCOSE MONITORING IN SUBCUTANEOUS TISSUE AND BLOOD WITH AN AMPEROMETRIC ENZYME ELECTRODE
Brückel, J. Zier, H. Kerner, W. Pfeiffer, E. F.
Brückel, J.
Zier, H.
Kerner, W.
Pfeiffer, E. F.
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Issue Date
1989
Submitted date
2023-12-06
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Abstract
As we have described previously, an amperometric enzyme electrode was developed, based on the detection of hydrogen peroxide generated by the oxidation of glucose (Kerner et al., Horm.Metab.Res.Suppl.20: 8-13,1988). This needle-type electrode was implanted into sc.tissue of sheep. It is shown that the sensor current is closely related to the course of blood glucose. For measurement of glucose in blood comparable to the Biostator, an electrode was further modified and integrated into a flow-chamber system. In vitro experiments demonstrated its qualification. Monitoring of blood glucose was performed over 24 hours.
Citation
Biosensors : applications in medicine, environmental protection and process control, 89 - 91
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Book chapter
conference paper
conference paper
Language
en
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Series/Report no.
GBF monographs ; Volume 13
ISSN
0930-4320
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ISBN
3527280324
0895739550
0895739550
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Attribution-NonCommercial-ShareAlike 4.0 International