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Generation and analysis of the improved human HAL9/10 antibody phage display libraries.
Kügler, Jonas ; Wilke, Sonja ; Meier, Doris ; Tomszak, Florian ; Frenzel, André ; Schirrmann, Thomas ; Dübel, Stefan ; Garritsen, Henk ; Hock, Björn ; Toleikis, Lars ... show 2 more
Kügler, Jonas
Wilke, Sonja
Meier, Doris
Tomszak, Florian
Frenzel, André
Schirrmann, Thomas
Dübel, Stefan
Garritsen, Henk
Hock, Björn
Toleikis, Lars
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Open Access publication
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Abstract
Antibody phage display is a proven key technology that allows the generation of human antibodies for diagnostics and therapy. From naive antibody gene libraries - in theory - antibodies against any target can be selected. Here we describe the design, construction and characterization of an optimized antibody phage display library.
Citation
Generation and analysis of the improved human HAL9/10 antibody phage display libraries. 2015, 15:10 BMC Biotechnol.
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Journal
PubMed ID
PubMed Central ID
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Article
Language
en
Description
Series/Report no.
ISSN
1472-6750
