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2020-11-20
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Abstract
The first total synthesis of halioxepine is accomplished using a 1,4-addition for constructing the quaternary center at C10 and a halo etherification for the generation of the tertiary ether at C7. The correct structure of halioxepine was determined by assembling different enantiomeric building blocks and by changing the relative configuration between C10 and C15.
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Chemistry. 2020 Nov 20. doi: 10.1002/chem.202004847.
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en
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1521-3765
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Attribution 4.0 International
