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Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells.
Lindenberg, Marc Solmaz, Gulhas Puttur, Franz
Lindenberg, Marc
Solmaz, Gulhas
Puttur, Franz
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Abstract
Cytomegalovirus establishes lifelong persistency in the host and leads to life threatening situations in immunocompromised patients. FoxP3+ T regulatory cells (Tregs) critically control and suppress innate and adaptive immune responses. However, their specific role during MCMV infection, especially pertaining to their interaction with NK cells, remains incompletely defined.
Citation
Mouse cytomegalovirus infection overrules T regulatory cell suppression on natural killer cells. 2014, 11:145 Virol. J.
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Journal
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PubMed Central ID
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Article
Language
en
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Series/Report no.
ISSN
1743-422X