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Immune Challenge Alters Reactivity of Hippocampal Noradrenergic System in Prenatally Stressed Aged Mice.
Grigoryan, Gayane Lonnemann, Niklas Korte, Martin
Grigoryan, Gayane
Lonnemann, Niklas
Korte, Martin
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2019-01-01
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Abstract
Prenatal stress (PS) has long-term sequelae for the morphological and functional status of the central nervous system of the progeny. A PS-induced proinflammatory status of the organism may result in an impairment of both hippocampal synaptic plasticity and hippocampus-dependent memory formation in adults. We addressed here the question of how PS-induced alterations in the immune response in young and old mice may contribute to changes in hippocampal function in aging. Immune stimulation (via
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Neural Plast. 2019 Jan 21;2019:3152129. doi: 10.1155/2019/3152129. eCollection 2019.
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en
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1687-5443
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Attribution-NonCommercial-ShareAlike 4.0 International