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Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers.
Köberle, Verena Pleli, Thomas Schmithals, Christian Augusto Alonso, Eduardo Haupenthal, Jörg Bönig, Halvard Peveling-Oberhag, Jan Biondi, Ricardo M Zeuzem, Stefan Kronenberger, Bernd
Köberle, Verena
Pleli, Thomas
Schmithals, Christian
Augusto Alonso, Eduardo
Haupenthal, Jörg
Bönig, Halvard
Peveling-Oberhag, Jan
Biondi, Ricardo M
Zeuzem, Stefan
Kronenberger, Bernd
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Abstract
MicroRNAs circulating in the blood, stabilized by complexation with proteins and/or additionally by encapsulation in lipid vesicles, are currently being evaluated as biomarkers. The consequences of their differential association with lipids/vesicles for their stability and use as biomarkers are largely unexplored and are subject of the present study.
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Differential Stability of Cell-Free Circulating microRNAs: Implications for Their Utilization as Biomarkers. 2013, 8 (9):e75184 PLoS ONE
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1932-6203
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