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The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis.

An Haack, Ira
; 
Derkow, Katja
; 
Riehn, Mathias
; 
Rentinck, Marc-Nicolas
; 
Kühl, Anja A
; 
Lehnardt, Seija
; 
Schott, Eckart
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Issue Date
2015
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Abstract
The role of regulatory CD4 T cells (Treg) in immune-mediated liver disease is still under debate. It remains disputed whether Treg suppress T cell-mediated hepatitis in vivo and whether hepatic regulatory T cells are functional in patients with autoimmune hepatitis.
Citation
The Role of Regulatory CD4 T Cells in Maintaining Tolerance in a Mouse Model of Autoimmune Hepatitis. 2015, 10 (11):e0143715 PLoS ONE
Affiliation
Dept. of Hepatology and Gastroenterology, Charité Universitätsmedizin Berlin, Berlin, Germany.
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Journal
PloS one
URI
http://hdl.handle.net/10033/615675
DOI
10.1371/journal.pone.0143715
PubMed ID
26599014
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Article
Language
en
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1932-6203
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publications of the research group modell systems for infections and immunity (MSYS)