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Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis.

Rohde, Manfred
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Chhatwal, G Singh
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2013
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Abstract
Streptococcal adhesion, invasion, intracellular trafficking, dissemination, and persistence in eukaryotic cells have a variety of implications in the infection pathogenesis. While cell adhesion establishes the initial host contact, adhering bacteria exploit the host cell for their own benefit. Internalization into the host cell is an essential step for bacterial survival and subsequent dissemination and persistence, thus playing a key role in the course of infection. This chapter summarizes the current knowledge about the diverse mechanisms of streptococcal adhesion to and invasion into different eukaryotic cells and the impact on dissemination and persistence which is reflected by consequences for the pathogenesis of streptococcal infections.
Citation
Adherence and invasion of streptococci to eukaryotic cells and their role in disease pathogenesis. 2013, 368:83-110 Curr. Top. Microbiol. Immunol.
Affiliation
Department of Medical Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany. manfred.rohde@helmholtz-hzi.de
Publisher
Journal
Current topics in microbiology and immunology
URI
http://hdl.handle.net/10033/297473
DOI
10.1007/82_2012_281
PubMed ID
23203001
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Book chapter
Language
en
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ISSN
0070-217X
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Archived with thanks to Current topics in microbiology and immunology
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Publications of Dept. Medizinische Mikrobiologie (MMIK)