Loading...
Arvoredol: An unusual chlorinated and biofilm inhibiting polyketide from a marine Penicillium sp. of the Brazilian coast
Scopel, Marina Mothes, Beatriz Lerner, Clea B. Henriques, Am?lia T. Macedo, Alexandre J.
Scopel, Marina
Mothes, Beatriz
Lerner, Clea B.
Henriques, Am?lia T.
Macedo, Alexandre J.
Citations
Altmetric:
Advisors
Editors
Other Contributors
Issue Date
2017-06
Submitted date
Files
Loading...
original manuscript
Adobe PDF, 1.66 MB
Other Titles
Abstract
Penicillium sp. F37 has been isolated from the marine sponge Axinella corrugata and shown to be closely related to Penicillium maximae. From the culture of Penicillium sp. F37 arvoredol, a novel chlorinated polyketide with 6,7-dihydro-4(5H)-benzofuranone moiety has been isolated and characterized by spectroscopic methods Arvoredol prevented biofilm formation of the human pathogen Staphylococcus epidermidis at a concentration of 125 μg mL−1 by 40%. It was also active against colorectal carcinoma HCT116 cells with a MIC of 7.9 μg mL−1. © 2017 Phytochemical Society of Europe
Citation
Arvoredol: An unusual chlorinated and biofilm inhibiting polyketide from a marine Penicillium sp. of the Brazilian coast 2017, 20:73 Phytochemistry Letters
Publisher
Journal
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
Description
Series/Report no.
ISSN
18743900