Loading...
PspA can form large scaffolds in Escherichia coli.
Standar, Kerstin Mehner, Denise Osadnik, Hendrik Berthelmann, Felix Hause, Gerd Lünsdorf, Heinrich Brüser, Thomas
Standar, Kerstin
Mehner, Denise
Osadnik, Hendrik
Berthelmann, Felix
Hause, Gerd
Lünsdorf, Heinrich
Brüser, Thomas
An error occurred retrieving the object's statistics
Citations
Altmetric:
Advisors
Editors
Other Contributors
Issue Date
2008-10-29
Submitted date
Files
Loading...
original manuscript
Adobe PDF, 2.18 MB
Other Titles
Abstract
The phage shock protein A (PspA) of Escherichia coli stabilizes the cytoplasmic membrane under stress conditions. Here we demonstrate that PspA can form hollow spherical or prolate spheroidal particles of about 30-40nm diameter with a scaffold-like arrangement of protein subunits at the surface. The 'PspA-scaffold' is the basic structure that is common to all particles. The PspA-scaffold may be of fundamental importance, as it could allow PspA to stabilize the integrity of membranes through numerous contact points over a large surface area.
Citation
PspA can form large scaffolds in Escherichia coli. 2008, 582 (25-26):3585-9 FEBS Lett.
Publisher
Journal
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
0014-5793