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Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.

Maahs, David M
; 
Siwy, Justyna
; 
Argilés, Angel
; 
Cerna, Marie
; 
Delles, Christian
; 
Dominiczak, Anna F
; 
Gayrard, Nathalie
; 
Iphöfer, Alexander
; ; 
Jerums, George
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2010
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Abstract
The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D).
Citation
Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. 2010, 5 (9) PLoS ONE
Affiliation
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, United States of America. David.Maahs@ucdenver.edu
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PloS one
URI
http://hdl.handle.net/10033/129760
DOI
10.1371/journal.pone.0013051
PubMed ID
20927192
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Article
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en
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1932-6203
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Publications of Dept. Cell Biology (ZB)