Loading...
Characterization of Microvesicles Released from Human Red Blood Cells.
Nguyen, Duc Bach Thuy Ly, Thi Bich Wesseling, Mauro Carlos Hittinger, Marius Torge, Afra Devitt, Andrew Perrie, Yvonne Bernhardt, Ingolf
Nguyen, Duc Bach
Thuy Ly, Thi Bich
Wesseling, Mauro Carlos
Hittinger, Marius
Torge, Afra
Devitt, Andrew
Perrie, Yvonne
Bernhardt, Ingolf
Files
Loading...
Open Access article
Adobe PDF, 1.85 MB
Other Titles
Abstract
Extracellular vesicles (EVs) are spherical fragments of cell membrane released from various cell types under physiological as well as pathological conditions. Based on their size and origin, EVs are classified as exosome, microvesicles (MVs) and apoptotic bodies. Recently, the release of MVs from human red blood cells (RBCs) under different conditions has been reported. MVs are released by outward budding and fission of the plasma membrane. However, the outward budding process itself, the release of MVs and the physical properties of these MVs have not been well investigated. The aim of this study is to investigate the formation process, isolation and characterization of MVs released from RBCs under conditions of stimulating Ca2+ uptake and activation of protein kinase C.
Citation
Characterization of Microvesicles Released from Human Red Blood Cells. 2016, 38 (3):1085-99 Cell. Physiol. Biochem.
Publisher
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
1421-9778