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Entry and replication of recombinant hepatitis C viruses in cell culture.

Vieyres, Gabrielle
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Pietschmann, Thomas
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2013-02
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Abstract
Hepatitis C virus (HCV) is a positive-strand enveloped RNA virus and belongs to the Flaviviridae family. The heavy health burden associated with the virus infection in humans and the intriguing peculiarities of the interaction between the HCV replication cycle and the hepatocyte host cell have stimulated a flourishing research field. The present review aims at recapitulating the different viral and cellular systems modelling HCV entry and replication, and in particular at gathering the tools available to dissect the HCV entry pathway.
Citation
Entry and replication of recombinant hepatitis C viruses in cell culture. 2013, 59 (2):233-48 Methods
Affiliation
Institute of Experimental Virology, TWINCORE, Centre for Experimental and Clinical Infection Research; A Joint Venture Between The Medical School Hannover and The Helmholtz Centre for Infection Research, Feodor-Lynen-Straße 7-9, 30625 Hannover, Germany.
Publisher
Journal
Methods (San Diego, Calif.)
URI
http://hdl.handle.net/10033/299086
DOI
10.1016/j.ymeth.2012.09.005
PubMed ID
23009812
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Article
Language
en
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ISSN
1095-9130
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Archived with thanks to Methods (San Diego, Calif.)
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publications of the work group experimental Virology([TC]EVIR)