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DIRECT OBSERVATION OF ANTI-ATRAZINE ANTIBODY BINDING USING GRATING COUPLERS
Bier, Frank F. Stöcklein, W. Schmid, Rolf D.
Bier, Frank F.
Stöcklein, W.
Schmid, Rolf D.
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Issue Date
1992
Submitted date
2024-04-17
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Adobe PDF, 1.87 MB
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Abstract
Planar monomode waveguides with grating couplers have beenapplied for the direct detection of anti-atrazine antibodies and a pesticide assay has been developed on the basis of a competitive immunoassay. Data are shown for the binding of anti-atrazine antibodiesin the concentration range from 1 to 10 ug/ml to an immobilized atrazine-derivative, corresponding to a changein the adlayer thickness of between 0.1 and 3 A. First competition experiments using terbutryn showed significant suppression of antibody binding at a concentration of 10 ng/ml.
Citation
Biosensors : fundamentals, technologies and applications, 205 - 208
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Book chapter
conference paper
conference paper
Language
en
Description
Series/Report no.
GBF monographs ; Volume 17
ISSN
0930-4320
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ISBN
3527284370
1560812206
1560812206
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Attribution-NonCommercial-ShareAlike 4.0 International