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Mimonoside D: a new triterpenoid saponin from Sauvalle (Fabaceae).
Kenmogne, Claudie Fokou Ponou, Beaudelaire Kemvoufo Kemkuignou, Blondelle Matio Kühlborn, Jonas Tchuenguem, Roland T Teponno, Rémy Bertrand Dzoyem, Jean Paul Opatz, Till Tapondjou, Léon Azefack
Kenmogne, Claudie Fokou
Ponou, Beaudelaire Kemvoufo
Kemkuignou, Blondelle Matio
Kühlborn, Jonas
Tchuenguem, Roland T
Teponno, Rémy Bertrand
Dzoyem, Jean Paul
Opatz, Till
Tapondjou, Léon Azefack
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2021-11-29
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A new triterpenoid saponin (Mimonoside D: 3-O-α-L-arabinopyranosyl-3β-hydroxyolean-12-en-28-oic acid 28-O-β-D-xylopyranosyl-(1→2)-β-D- glucopyranoside ester (1)) was isolated from the aerial parts of Mimosa diplotricha Sauvalle together with nine known compounds: 7,4'-dihydroxyflavone (2), kaempferol (3), lupeol (4), betulinic acid (5), β-sitosterol (6), β-sitosterol-3-O-β-D-glucopyranoside (7), lutein (8), 5,2'-dihydroxy-7,4',5'-trimethoxyflavone (9) and vitexin (10). Their structures were elucidated on the basis of spectroscopic (1 D and 2 D nuclear magnetic resonance) and high-resolution mass spectrometric data as well as by comparison of their spectral data with those of related compounds. Compounds 2, 7 and 8 had already been isolated from M. diplotricha, while compounds 3, 4, 5 and 6 have been isolated from other Mimosa species. Compound 2 moderately inhibited Proteus mirabilis (MIC = 32 µg/mL), weakly inhibited Pseudomonas aeruginosa (MIC = 64 µg/mL) and very weakly inhibited Staphylococcus aureus (MIC = 128 µg/mL) and Enterococus faecalis (MIC = 128 µg/mL).
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Nat Prod Res. 2021 Nov 29:1-9. doi: 10.1080/14786419.2021.2008386. Epub ahead of print.
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en
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1478-6427
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Attribution-NonCommercial 4.0 International