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Birth, evolution, and transmission of satellite-free mammalian centromeric domains.

Nergadze, Solomon G
Piras, Francesca M
Gamba, Riccardo
Corbo, Marco
Cerutti, Federico
McCarter, Joseph G W
Cappelletti, Eleonora
Gozzo, Francesco
Harman, Rebecca M
Antczak, Douglas F
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2018-01-01
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Mammalian centromeres are associated with highly repetitive DNA (satellite DNA), which has so far hindered molecular analysis of this chromatin domain. Centromeres are epigenetically specified, and binding of the CENPA protein is their main determinant. In previous work, we described the first example of a natural satellite-free centromere on
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1549-5469
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Attribution-NonCommercial-ShareAlike 3.0 United States