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Regulatory T-Cells Mediate IFN-α-Induced Resistance against Antigen-Induced Arthritis.

Chenna Narendra, Sudeep
; 
Chalise, Jaya Prakash
; 
Biggs, Sophie
; ; 
Magnusson, Mattias
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Issue Date
2018-01-01
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Abstract
CD4 Arthritis was triggered by intra-articular injection of methylated bovine serum albumin (mBSA) in wild-type mice, Foxp3DTReGFP Both control mice and mice devoid of IFNAR-signaling in T helper cells were protected from arthritis by IFN-α. Depletion of T By activating IDO during antigen sensitization, IFN-α activates T
Citation
Affiliation
TWINCORE, Zentrum für experimentelle und klinische Infektionsforschung GmbH,Feodor-Lynen Str. 7, 30625 Hannover, Germany.
Publisher
Frontiers
Journal
URI
http://hdl.handle.net/10033/621593
DOI
10.3389/fimmu.2018.00285
PubMed ID
29515584
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Article
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ISSN
1664-3224
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Attribution-NonCommercial-ShareAlike 4.0 International
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publications of the research group of experimental infection research([TC] EXPI)