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Remodeling of the Carbohydrate Chains of hCG by Use of Sialyltransferases: Effects on the Biological Activity
Nemansky, Martin Eijnden, Dirk H. van den Dedem, Gijs W. K. van Mannaerts, Bernadette M. J. L.
Nemansky, Martin
Eijnden, Dirk H. van den
Dedem, Gijs W. K. van
Mannaerts, Bernadette M. J. L.
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Issue Date
1991
Submitted date
2024-02-28
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Abstract
Human chorionic gonadotropin (hCG) is a glycoprotein hormone which contains both N- and O-linked carbohydrate chains. It consists of two subunits, a and 8. The a-subunit contains two N-linked carbohydrate chains: a mono-antenna and a non-fucosylated bi-antenna. The $-subunit contains both (two) N and (four) O-linked carbohydrate structures. Both of the N-linked carbohydrate chainsare biantennary, one of which is fucosylated.
Citation
Protein glycosylation, 221 - 222
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Book chapter
conference paper
conference paper
Language
en
Description
Series/Report no.
GBF monographs ; Volume 15
ISSN
0930-4320
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ISBN
1560811846
3527283676
3527283676
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Attribution-NonCommercial-ShareAlike 4.0 International