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Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection.
Bihrer, Verena Friedrich-Rust, Mireen Kronenberger, Bernd Forestier, Nicole Haupenthal, Jörg Shi, Ying Peveling-Oberhag, Jan Radeke, Heinfried H Sarrazin, Christoph Herrmann, Eva
Bihrer, Verena
Friedrich-Rust, Mireen
Kronenberger, Bernd
Forestier, Nicole
Haupenthal, Jörg
Shi, Ying
Peveling-Oberhag, Jan
Radeke, Heinfried H
Sarrazin, Christoph
Herrmann, Eva
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2011-09
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Abstract
The liver contains large amounts of microRNA-122 (miR-122), whereas other tissues contain only marginal amounts of this miRNA. MicroRNAs have also been found to circulate in the blood in a cell-free form; their potential as readily accessible disease markers is currently evaluated. Here, we investigated if the serum levels of miR-122 might be useful as disease parameter in patients with chronic hepatitis C virus (HCV) infection.
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Serum miR-122 as a biomarker of necroinflammation in patients with chronic hepatitis C virus infection. 2011, 106 (9):1663-9 Am. J. Gastroenterol.
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Article
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en
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1572-0241