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Characterization of JG024, a pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions.
Garbe, Julia ; Wesche, Andrea ; Bunk, Boyke ; Kazmierczak, Marlon ; Selezska, Katherina ; Rohde, Christine ; Sikorski, Johannes ; Rohde, Manfred ; Jahn, Dieter ; Schobert, Max
Garbe, Julia
Wesche, Andrea
Bunk, Boyke
Kazmierczak, Marlon
Selezska, Katherina
Rohde, Christine
Sikorski, Johannes
Rohde, Manfred
Jahn, Dieter
Schobert, Max
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Abstract
Pseudomonas aeruginosa causes lung infections in patients suffering from the genetic disorder Cystic Fibrosis (CF). Once a chronic lung infection is established, P. aeruginosa cannot be eradicated by antibiotic treatment. Phage therapy is an alternative to treat these chronic P. aeruginosa infections. However, little is known about the factors which influence phage infection of P. aeruginosa under infection conditions and suitable broad host range phages.
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Characterization of JG024, a pseudomonas aeruginosa PB1-like broad host range phage under simulated infection conditions. 2010, 10:301 BMC Microbiol.
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en
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1471-2180
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