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BUILDING BLOCKS FOR THE CHEMICAL SYNTHESIS OF DNA CONTAINING C(3')-CH2-P BONDS

Morr, Michael
Ernst, Ludger
Kakoschke, Christel
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Issue Date
1987
Submitted date
2023-04-26
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Abstract
The preparation, starting from glucose, of 3'-[ (2-chlorophenoxy)phosphinylmethyl]- N2-isobutyryl-5'-0-(4-methoxytrityl)-2' ,3'-dideoxyguanosine ts described. Applying established phosphotriester methods, 21 was used to synthesize a phosphonate analogue of the dinucleotide monophosphate d(G-C).
Citation
Chemical synthesis in molecular biology, 107 ff
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Book chapter
conference paper
Language
en
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Series/Report no.
GBF Monographs, Vol. 8
ISSN
0930-4320
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Attribution-NonCommercial-ShareAlike 4.0 International