Loading...
Analogs of the carotane antibiotic fulvoferruginin from submerged cultures of a Thai sp.
Sandargo, Birthe Kaysan, Leon Teponno, Rémy B Richter, Christian Thongbai, Benjarong Surup, Frank Stadler, Marc
Sandargo, Birthe
Kaysan, Leon
Teponno, Rémy B
Richter, Christian
Thongbai, Benjarong
Surup, Frank
Stadler, Marc
Citations
Altmetric:
Advisors
Editors
Other Contributors
Issue Date
2021-06-04
Submitted date
Files
Loading...
Open Access publication
Adobe PDF, 349.6 KB
Other Titles
Abstract
A recent find of a Marasmius species in Northern Thailand led to the isolation of five unprecedented derivatives of the carotane antibiotic fulvoferruginin (1), fulvoferruginins B-F (2-6). The structures of these sesquiterpenoids were elucidated using HRESIMS, 1D and 2D NMR, as well as CD spectroscopy. Assessing the bioactivity, fulvoferruginin emerged as a potent cytotoxic agent of potential pharmaceutical interest.
Citation
Beilstein J Org Chem. 2021 Jun 4;17:1385-1391. doi: 10.3762/bjoc.17.97.
Publisher
PubMed ID
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
1860-5397
EISSN
ISBN
ISMN
Gov't Doc #
Sponsors
License
Attribution 4.0 International