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Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus.
Bokkasam, Harish Ernst, Matthias Guenther, Marco Wagner, Christian Schaefer, Ulrich F Lehr, Claus-Michael
Bokkasam, Harish
Ernst, Matthias
Guenther, Marco
Wagner, Christian
Schaefer, Ulrich F
Lehr, Claus-Michael
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2016-06-13
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Abstract
Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate-plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus.
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Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus. 2016: Int J Pharm
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1873-3476