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[Lung function in the German National Cohort: methods and initial results].
Karrasch, Stefan Peters, Annette Meisinger, Christa Ferland, Maike Jaeschke, Lina Pischon, Tobias Fricke, Julia Keil, Thomas Gastell, Sylvia Schulze, Matthias
Karrasch, Stefan
Peters, Annette
Meisinger, Christa
Ferland, Maike
Jaeschke, Lina
Pischon, Tobias
Fricke, Julia
Keil, Thomas
Gastell, Sylvia
Schulze, Matthias
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2020-03-01
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Abstract
In the present dataset (n = 101,734), spirometry was available for 86,893 study participants and FeNO was available for 15,228 participants. The average (±SD) FEV1 Z score (according to GLI 2012) was -0.321 ± 1.047, the FVC Z score was -0.153 ± 0.941, and the FEV1/FVC Z score was -0.337 ± 0.901. The difference in FEV1/FVC between current smokers and never-smokers increased with age. The average FeNO was 14.2 ÷ 2.0 ppb. Current smoking reduced FeNO levels by 43%, whereas respiratory allergy increased FeNO levels by 16% in nonsmokers.
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Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2020 Mar;63(3):322-331. doi: 10.1007/s00103-020-03102-1.
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en
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1437-1588
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Attribution-NonCommercial-ShareAlike 4.0 International