Thumbnail Image
Publication

The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo.

Kukita, Akiko
; 
Kukita, Toshio
; 
Nagata, Kengo
; 
Teramachi, Junpei
; 
Li, Yin-Ji
; 
Yoshida, Hiroki
; 
Miyamoto, Hiroshi
; 
Gay, Steffen
; 
Pessler, Frank
; 
Shobuike, Takeo
Citations
Altmetric:
Advisors
Editors
Other Contributors
Issue Date
2011-09
Submitted date
Show all metadata
Files
Thumbnail Image
original manuscript
Adobe PDF, 4.72 MB
Other Titles
Abstract
Since transcription factors expressed in osteoclasts are possible targets for regulation of bone destruction in bone disorders, we investigated the expression of the transcription factor FBI-1/OCZF/LRF (in humans, factor that binds to inducer of short transcripts of human immunodeficiency virus type 1; in rats, osteoclast-derived zinc finger; in mice, leukemia/lymphoma-related factor) in patients with rheumatoid arthritis (RA), and assessed its role in osteoclastogenesis in vivo.
Citation
The transcription factor FBI-1/OCZF/LRF is expressed in osteoclasts and regulates RANKL-induced osteoclast formation in vitro and in vivo. 2011, 63 (9):2744-54 Arthritis Rheum.
Affiliation
Department of Microbiology, Faculty of Medicine, Saga University, Saga, Japan. kukita@cc.saga-u.ac.jp
Publisher
Journal
Arthritis and rheumatism
URI
http://hdl.handle.net/10033/214592
DOI
10.1002/art.30455
PubMed ID
21590684
PubMed Central ID
Additional Links
Embedded video
Type
Article
Language
en
Description
Series/Report no.
ISSN
1529-0131
EISSN
ISBN
ISMN
Gov't Doc #
Sponsors
License
Collections
publications of the research group of epidemiology (EPID)