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How distinct Arp2/3 complex variants regulate actin filament assembly.

Rottner, Klemens
; 
Stradal, Theresia E B
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Issue Date
2015-12-23
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Abstract
The heptameric Arp2/3 complex generates branched actin filament networks that drive lamellipodium protrusion, vesicle trafficking and pathogen motility. Distinct variants of the Arp2/3 complex are now shown to have different roles in tuning actin assembly and disassembly, in concert with the prominent actin regulators cortactin and coronin.
Citation
How distinct Arp2/3 complex variants regulate actin filament assembly. 2015, 18 (1):1-3 Nat. Cell Biol.
Affiliation
Helmholtz Centre for infection research, Inhoffenstr. 7, D-38124 Braunschweig, Germany.
Publisher
Journal
Nature cell biology
URI
http://hdl.handle.net/10033/596375
DOI
10.1038/ncb3293
PubMed ID
26693915
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Article
Language
en
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ISSN
1476-4679
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publications of the research group cell biology (ZBIO)
publications of the Research group: molecular cell biology (MZBI)