Department of Microbial Drugs (MWIS)
http://hdl.handle.net/10033/620857
2024-03-29T06:01:42Z
2024-03-29T06:01:42Z
Author Correction: The planctomycete Stieleria maiorica Mal15 employs stieleriacines to alter the species composition in marine biofilms.
Kallscheuer, Nicolai
Jeske, Olga
Sandargo, Birthe
Boedeker, Christian
Wiegand, Sandra
Bartling, Pascal
Jogler, Mareike
Rohde, Manfred
Petersen, Jörn
Medema, Marnix H
Surup, Frank
Jogler, Christian
http://hdl.handle.net/10033/623215
2022-06-14T01:57:03Z
2020-08-31T00:00:00Z
Author Correction: The planctomycete Stieleria maiorica Mal15 employs stieleriacines to alter the species composition in marine biofilms.
Kallscheuer, Nicolai; Jeske, Olga; Sandargo, Birthe; Boedeker, Christian; Wiegand, Sandra; Bartling, Pascal; Jogler, Mareike; Rohde, Manfred; Petersen, Jörn; Medema, Marnix H; Surup, Frank; Jogler, Christian
2020-08-31T00:00:00Z
RNAi-based system a new tool for insects’ control
Gacem, Mohamed Amine
Boukerouis, Djoudi
Telli, Alia
Ould-El-Hadj-Khelil, Aminata
Wink, Joachim
http://hdl.handle.net/10033/623195
2022-06-14T01:56:38Z
2021-03-05T00:00:00Z
RNAi-based system a new tool for insects’ control
Gacem, Mohamed Amine; Boukerouis, Djoudi; Telli, Alia; Ould-El-Hadj-Khelil, Aminata; Wink, Joachim
One of the molecular devices practised recently has been the fusion of RNA interference (RNAi) into some agricultural products. It is a definite genetic controlling system recognized in eukaryotes. Through this system, certain exogenous pathogens are neutralized by deactivating the expression of target genes. The decisive factor for the progress of this gene defence machinery is the double-stranded RNA (dsRNA). The effectiveness and specificity of the RNAi tool in gene silencing have been approved with great precision in small-scale guide tests. The development of this molecular tool as bioinsecticides has started to attract the biotechnology industries. Once the safety and certainty actions respecting the regulatory framework are established by researchers and biotechnology industries for crop protection, for example, sustainability and particularity of defence, develop new resistant cultivars against plant pests, and removal of all unexpected effects on the environment, genetically modified crops incorporating dsRNA can be marketed. The current chapter discusses the RNAi tool and its role in protecting crops from insect pest attacks, dsRNA transfer methods in plant cells, and critical points affecting the achievement of the molecular tool. Finally, some environmental risks identified in the small-scale guide tests are discussed.
2021-03-05T00:00:00Z
CRISPR-Cas systems as antimicrobial agents for agri-food pathogens
Amine, Gacem Mohamed
Gacem, Hiba
Boukerouis, Djoudi
Wink, Joachim
Gacem, Mohamed Amine
http://hdl.handle.net/10033/623194
2022-06-14T01:56:50Z
2021-03-05T00:00:00Z
CRISPR-Cas systems as antimicrobial agents for agri-food pathogens
Amine, Gacem Mohamed; Gacem, Hiba; Boukerouis, Djoudi; Wink, Joachim; Gacem, Mohamed Amine
The CRISPR-Cas (clustered regularly interspaced short palindromic repeat-CRISPR-associated sequences) systems identified in microorganisms are very diverse in their functional organization and mechanism. They participate in the illustration of the development of the strain that carries them over time. The reason is that each time an exogenous genetic fragment is encountered, a spacer is acquired and then inserted into the CRISPR array. These spacers can provide very important historical information on external aggressors, their ecology, and geography. This complex arrangement has a dynamic protection and defense capacity against exogenous genetic elements, which gives the bacterial cell better protection. On the genomic level, the understanding of its functional mechanism is a key factor in its exploitation as a molecular biology and genome editing tool. This chapter aims at clarifying the applications of the CRISPR/Cas system in the preservation and security of crops and food against viral, fungal, and bacterial alterations. © 2021 Elsevier Inc. All rights reserved.
name of first author & corresponding author is:
Gacem, Mohamed Amine (not Amine, Gacem Mohamed as indicated at publisher's page)
2021-03-05T00:00:00Z
Mimonoside D: a new triterpenoid saponin from Sauvalle (Fabaceae).
Kenmogne, Claudie Fokou
Ponou, Beaudelaire Kemvoufo
Kemkuignou, Blondelle Matio
Kühlborn, Jonas
Tchuenguem, Roland T
Teponno, Rémy Bertrand
Dzoyem, Jean Paul
Opatz, Till
Tapondjou, Léon Azefack
http://hdl.handle.net/10033/623152
2022-02-02T09:20:03Z
2021-11-29T00:00:00Z
Mimonoside D: a new triterpenoid saponin from Sauvalle (Fabaceae).
Kenmogne, Claudie Fokou; Ponou, Beaudelaire Kemvoufo; Kemkuignou, Blondelle Matio; Kühlborn, Jonas; Tchuenguem, Roland T; Teponno, Rémy Bertrand; Dzoyem, Jean Paul; Opatz, Till; Tapondjou, Léon Azefack
A new triterpenoid saponin (Mimonoside D: 3-O-α-L-arabinopyranosyl-3β-hydroxyolean-12-en-28-oic acid 28-O-β-D-xylopyranosyl-(1→2)-β-D- glucopyranoside ester (1)) was isolated from the aerial parts of Mimosa diplotricha Sauvalle together with nine known compounds: 7,4'-dihydroxyflavone (2), kaempferol (3), lupeol (4), betulinic acid (5), β-sitosterol (6), β-sitosterol-3-O-β-D-glucopyranoside (7), lutein (8), 5,2'-dihydroxy-7,4',5'-trimethoxyflavone (9) and vitexin (10). Their structures were elucidated on the basis of spectroscopic (1 D and 2 D nuclear magnetic resonance) and high-resolution mass spectrometric data as well as by comparison of their spectral data with those of related compounds. Compounds 2, 7 and 8 had already been isolated from M. diplotricha, while compounds 3, 4, 5 and 6 have been isolated from other Mimosa species. Compound 2 moderately inhibited Proteus mirabilis (MIC = 32 µg/mL), weakly inhibited Pseudomonas aeruginosa (MIC = 64 µg/mL) and very weakly inhibited Staphylococcus aureus (MIC = 128 µg/mL) and Enterococus faecalis (MIC = 128 µg/mL).
2021-11-29T00:00:00Z