Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci, southern India.

Reissmann, Silvana; Friedrichs, Claudia; Rajkumari, Reena; Itzek, Andreas; Fulde, Marcus; Rodloff, Arne C; Brahmadathan, Kootallur N; Chhatwal, Gursharan S; Nitsche-Schmitz, D Patric

dc.contributor.author	Reissmann, Silvana
dc.contributor.author	Friedrichs, Claudia
dc.contributor.author	Rajkumari, Reena
dc.contributor.author	Itzek, Andreas
dc.contributor.author	Fulde, Marcus
dc.contributor.author	Rodloff, Arne C
dc.contributor.author	Brahmadathan, Kootallur N
dc.contributor.author	Chhatwal, Gursharan S
dc.contributor.author	Nitsche-Schmitz, D Patric
dc.date.accessioned	2010-06-24T09:36:11Z
dc.date.available	2010-06-24T09:36:11Z
dc.date.issued	2010-04
dc.identifier.citation	Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci, southern India. 2010, 16 (4):656-63 Emerging Infect. Dis.	en
dc.identifier.issn	1080-6059
dc.identifier.pmid	20350380
dc.identifier.uri	http://hdl.handle.net/10033/106778
dc.description.abstract	Vellore, a region in southern India, has a high incidence of severe human infections with Beta-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006-2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.
dc.language.iso	en	en
dc.subject.mesh	DNA, Bacterial	en
dc.subject.mesh	Genes, Bacterial	en
dc.subject.mesh	Genetic Markers	en
dc.subject.mesh	Humans	en
dc.subject.mesh	India	en
dc.subject.mesh	Open Reading Frames	en
dc.subject.mesh	Polymerase Chain Reaction	en
dc.subject.mesh	RNA, Ribosomal, 16S	en
dc.subject.mesh	Sequence Analysis, DNA	en
dc.subject.mesh	Streptococcal Infections	en
dc.subject.mesh	Streptococcus	en
dc.subject.mesh	Streptococcus anginosus	en
dc.subject.mesh	Streptococcus constellatus	en
dc.subject.mesh	Virulence Factors	en
dc.title	Contribution of Streptococcus anginosus to infections caused by groups C and G streptococci, southern India.	en
dc.type	Article	en
dc.contributor.department	Helmholtz Centre for Infection Research, Braunschweig, Germany.	en
dc.identifier.journal	Emerging infectious diseases	en
refterms.dateFOA	2018-06-13T00:56:20Z
html.description.abstract	Vellore, a region in southern India, has a high incidence of severe human infections with Beta-hemolytic group C and G streptococci (GCGS). To determine the causative species in these infections, we conducted 16S rRNA gene sequencing: Streptococcus dysgalactiae subsp. equisimilis (81%) and S. anginosus (19%) were the causative organisms in the 2-year study period (2006-2007). We used PCR to detect the virulence-related emm gene; results showed that it was restricted to S. dysgalactieae subsp. equisimilis isolates of 99.2% tested positive. Due to a novel marker, S. anginosus and S. constellatus can be quickly and accurately distinguished from other members of the genus. The notable contribution of the anginosus group to human infections suggests that this group of obligate pathogens deserves more attention in healthcare and research.