• Login
    View Item 
    •   Home
    • Division of Microbiology (MIK)
    • Publications of Division of Microbiology (MIK)
    • View Item
    •   Home
    • Division of Microbiology (MIK)
    • Publications of Division of Microbiology (MIK)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of HZICommunitiesTitleAuthorsIssue DateSubmit DateSubjectsJournalTypesSubject (MeSH)This CollectionTitleAuthorsIssue DateSubmit DateSubjectsJournalTypesSubject (MeSH)

    My Account

    LoginRegister

    Local Links

    About: PolicyHelmholtz-Zentrum für Infektionsforschung HomepageHZI-Library HomepageContact usOpen AccessPublishing ApproachGetting StartedEditing ProfileBrowsing OptionsUsing SearchSubmitting ContentLicenced Journals & access details here

    Statistics

    Display statistics

    7-O-malonyl macrolactin A, a new macrolactin antibiotic from Bacillus subtilis active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and a small-colony variant of Burkholderia cepacia.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Molinari_AAC.pdf
    Size:
    6.877Mb
    Format:
    PDF
    Description:
    original document
    Download
    Average rating
     
       votes
    Cast your vote
    You can rate an item by clicking the amount of stars they wish to award to this item. When enough users have cast their vote on this item, the average rating will also be shown.
    Star rating
     
    Your vote was cast
    Thank you for your feedback
    Authors
    Romero-Tabarez, Magally
    Jansen, Rolf
    Sylla, Marita
    Lünsdorf, Heinrich
    Häussler, Susanne
    Santosa, Dwi A
    Timmis, Kenneth N
    Molinari, Gabriella
    Issue Date
    2006-05-01
    
    Metadata
    Show full item record
    Abstract
    We report here the discovery, isolation, and chemical and preliminary biological characterization of a new antibiotic compound, 7-O-malonyl macrolactin A (MMA), produced by a Bacillus subtilis soil isolate. MMA is a bacteriostatic antibiotic that inhibits a number of multidrug-resistant gram-positive bacterial pathogens, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and a small-colony variant of Burkholderia cepacia. MMA-treated staphylococci and enterococci were pseudomulticellular and exhibited multiple asymmetric initiation points of septum formation, indicating that MMA may inhibit a cell division function.
    Citation
    Antimicrob. Agents Chemother. 2006, 50(5):1701-9
    URI
    http://hdl.handle.net/10033/12307
    DOI
    10.1128/AAC.50.5.1701-1709.2006
    PubMed ID
    16641438
    Type
    Article
    Language
    en
    ISSN
    0066-4804
    ae974a485f413a2113503eed53cd6c53
    10.1128/AAC.50.5.1701-1709.2006
    Scopus Count
    Collections
    Publications of Division of Microbiology (MIK)

    entitlement

    Related articles

    • Antibacterial activities of macrolactin A and 7-O-succinyl macrolactin A from Bacillus polyfermenticus KJS-2 against vancomycin-resistant enterococci and methicillin-resistant Staphylococcus aureus.
    • Authors: Kim DH, Kim HK, Kim KM, Kim CK, Jeong MH, Ko CY, Moon KH, Kang JS
    • Issue date: 2011 Jan
    • In vitro activity of tigecycline against quinolone-resistant Streptococcus pneumoniae, methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci.
    • Authors: Garrison MW, Nuemiller JJ
    • Issue date: 2007 Feb
    • Activity of daptomycin against multi-resistant Gram-positive bacteria including enterococci and Staphylococcus aureus resistant to linezolid.
    • Authors: Johnson AP, Mushtaq S, Warner M, Livermore DM
    • Issue date: 2004 Oct
    • Macrolactin N, a new peptide deformylase inhibitor produced by Bacillus subtilis.
    • Authors: Yoo JS, Zheng CJ, Lee S, Kwak JH, Kim WG
    • Issue date: 2006 Sep 15
    • A novel antibacterial iridoid and triterpene from Caiophora coronata.
    • Authors: Khera S, Woldemichael GM, Singh MP, Suarez E, Timmermann BN
    • Issue date: 2003 Dec

    DSpace software copyright © 2002-2022  DuraSpace
    Quick Guide | Kontakt | Feedback abschicken
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.