Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O.
| dc.contributor.author | Gekara, Nelson O | |
| dc.contributor.author | Zietara, Natalia | |
| dc.contributor.author | Geffers, Robert | |
| dc.contributor.author | Weiss, Siegfried | |
| dc.date.accessioned | 2011-03-30T09:08:20Z | |
| dc.date.available | 2011-03-30T09:08:20Z | |
| dc.date.issued | 2010-12-01 | |
| dc.identifier.citation | Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. 2010, 202 (11):1698-707 J. Infect. Dis. | en |
| dc.identifier.issn | 1537-6613 | |
| dc.identifier.pmid | 20961225 | |
| dc.identifier.doi | 10.1086/657145 | |
| dc.identifier.uri | http://hdl.handle.net/10033/126271 | |
| dc.description.abstract | The success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes. | |
| dc.language.iso | en | en |
| dc.subject.mesh | Animals | en |
| dc.subject.mesh | Bacterial Toxins | en |
| dc.subject.mesh | CD4-Positive T-Lymphocytes | en |
| dc.subject.mesh | Disease Models, Animal | en |
| dc.subject.mesh | Flow Cytometry | en |
| dc.subject.mesh | Gene Expression | en |
| dc.subject.mesh | Heat-Shock Proteins | en |
| dc.subject.mesh | Hemolysin Proteins | en |
| dc.subject.mesh | Listeria monocytogenes | en |
| dc.subject.mesh | Mice | en |
| dc.subject.mesh | Mice, Inbred C57BL | en |
| dc.subject.mesh | Microarray Analysis | en |
| dc.subject.mesh | Receptors, Antigen, T-Cell | en |
| dc.subject.mesh | Specific Pathogen-Free Organisms | en |
| dc.title | Listeria monocytogenes induces T cell receptor unresponsiveness through pore-forming toxin listeriolysin O. | en |
| dc.type | Article | en |
| dc.contributor.department | Molecular Immunology, Helmholtz Center for Infection Research, Braunschweig, Germany. nelson.gekara@mims.umu.se | en |
| dc.identifier.journal | The Journal of infectious diseases | en |
| refterms.dateFOA | 2011-12-15T00:00:00Z | |
| html.description.abstract | The success of many pathogens relies on their ability to circumvent the innate and adaptive immune defenses. How bacterial pathogens subvert adaptive immune defenses is not clear. Cholesterol-dependent cytolysins (CDCs) represent an expansive family of homologous pore-forming toxins that are produced by more than 20 gram-positive bacterial species. Listeriolysin O (LLO), a prototype CDC, is the main virulence factor of Listeria monocytogenes. |
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