Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology.
dc.contributor.author | Maahs, David M | |
dc.contributor.author | Siwy, Justyna | |
dc.contributor.author | Argilés, Angel | |
dc.contributor.author | Cerna, Marie | |
dc.contributor.author | Delles, Christian | |
dc.contributor.author | Dominiczak, Anna F | |
dc.contributor.author | Gayrard, Nathalie | |
dc.contributor.author | Iphöfer, Alexander | |
dc.contributor.author | Jänsch, Lothar | |
dc.contributor.author | Jerums, George | |
dc.contributor.author | Medek, Karel | |
dc.contributor.author | Mischak, Harald | |
dc.contributor.author | Navis, Gerjan J | |
dc.contributor.author | Roob, Johannes M | |
dc.contributor.author | Rossing, Kasper | |
dc.contributor.author | Rossing, Peter | |
dc.contributor.author | Rychlík, Ivan | |
dc.contributor.author | Schiffer, Eric | |
dc.contributor.author | Schmieder, Roland E | |
dc.contributor.author | Wascher, Thomas C | |
dc.contributor.author | Winklhofer-Roob, Brigitte M | |
dc.contributor.author | Zimmerli, Lukas U | |
dc.contributor.author | Zürbig, Petra | |
dc.contributor.author | Snell-Bergeon, Janet K | |
dc.date.accessioned | 2011-05-18T13:44:55Z | en |
dc.date.available | 2011-05-18T13:44:55Z | en |
dc.date.issued | 2010 | en |
dc.identifier.citation | Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. 2010, 5 (9) PLoS ONE | en |
dc.identifier.issn | 1932-6203 | en |
dc.identifier.pmid | 20927192 | en |
dc.identifier.doi | 10.1371/journal.pone.0013051 | en |
dc.identifier.uri | http://hdl.handle.net/10033/129760 | en |
dc.description.abstract | The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D). | |
dc.language.iso | en | en |
dc.subject.mesh | Adult | en |
dc.subject.mesh | Biological Markers | en |
dc.subject.mesh | Cohort Studies | en |
dc.subject.mesh | Collagen | en |
dc.subject.mesh | Diabetes Mellitus, Type 1 | en |
dc.subject.mesh | Diabetes Mellitus, Type 2 | en |
dc.subject.mesh | Extracellular Matrix | en |
dc.subject.mesh | Female | en |
dc.subject.mesh | Humans | en |
dc.subject.mesh | Male | en |
dc.subject.mesh | Mass Spectrometry | en |
dc.subject.mesh | Middle Aged | en |
dc.subject.mesh | Proteomics | en |
dc.title | Urinary collagen fragments are significantly altered in diabetes: a link to pathophysiology. | en |
dc.type | Article | en |
dc.contributor.department | Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, United States of America. David.Maahs@ucdenver.edu | en |
dc.identifier.journal | PloS one | en |
refterms.dateFOA | 2018-06-13T00:11:35Z | |
html.description.abstract | The pathogenesis of diabetes mellitus (DM) is variable, comprising different inflammatory and immune responses. Proteome analysis holds the promise of delivering insight into the pathophysiological changes associated with diabetes. Recently, we identified and validated urinary proteomics biomarkers for diabetes. Based on these initial findings, we aimed to further validate urinary proteomics biomarkers specific for diabetes in general, and particularity associated with either type 1 (T1D) or type 2 diabetes (T2D). |